Question: Good morning! "Two years ago I underwent a course of treatment for CMV, but felt no relief. Several times a year poyavlyuyatsya rash genetaliyah. Now I am pregnant. Tests for CMV negative. But even so there are eruptions. Approximately 2 months were sechas in the fifth. Maybe, if a child is born with cerebral palsy and install-it ultrasound? Thank you.
Answer: Cytomegalovirus infection is particularly dangerous during pregnancy. This danger is caused by the fact that the risk of transmission of cytomegalovirus from mother to fetus is very large. CMV is one of the first places in utero infection of the fetus. Particularly severe impact can cause the transfer of primary infection, when CMV was in the mother for the first time during pregnancy. Women, therefore, in the blood which in the analysis were not detected antibodies to cytomegalovirus, are a risk group and should be particularly careful to care for the prevention of cytomegalovirus infection. Therefore, cytomegalovirus infection, along with rubella, toxoplasmosis, and herpes is included in the group of diseases to which women better screened before conception. Fetal cytomegalovirus infection can occur in different ways. Fruit can be infected at the time of conception, as well as cytomegalovirus and contained in the male seed. Cytomegalovirus infection can penetrate into the body of the child through the placenta during pregnancy. More frequently, only CMV enters the unborn child from the uterus through the fetal membranes. In addition, cytomegalovirus infection can occur during childbirth, at the moment when the child ancestral pathways or after birth through breastfeeding, as well as cytomegalovirus and located in the mucosa of the vagina, through which passes a child, and in breast milk of women infected. However, it should be noted that cytomegalovirus infection of the child during birth and after is not so dangerous and does not lead to such terrible consequences, such as intrauterine infection. When the fetus is infected during pregnancy, there are several possible options for future development: Fetal cytomegalovirus infection can develop without symptoms, without consequences for the health of the child. Of course, this option can be considered optimal for this situation, since it likely to give birth to a healthy baby is very large. After birth, the baby will become as a passive carrier of cytomegalovirus, like many people living for many years and have no idea about that are infected with HIV. Cytomegalovirus inside the body of the fruit in this case may lead to low birth weight. In the future it may develop normally, catching up with their peers, and can keep up with them on a number of indicators. Heavier version – when cytomegalovirus, has infected the fetus in utero, provokes the development of severe infection, leading to fetal death (miscarriages, spontaneous abortions, stillbirths). Usually, such a characteristic of CMV infection of the fetus in early pregnancy, usually before 12 weeks of pregnancy. If the fetus survives after infection with cytomegalovirus or infection occurs in the later stages of pregnancy, the child may be born with congenital cytomegalovirus infection. It manifests itself immediately after birth malformations, including underdeveloped brain, hydrocephalus, hepatitis, jaundice, enlargement of the liver and spleen, pneumonia, heart defects, congenital deformities. Born a child may suffer mental retardation, deafness, epilepsy, cerebral palsy, muscular weakness. In other cases, congenital CMV occurs only at the 2-5-th year of life of the infected child's blindness, deafness, speech inhibition, retardation, psychomotor disturbances. In connection with the possibility of all such violations of cytomegalovirus infection during pregnancy is, in some cases, indications for the artificial termination. This doctor's decision, leading pregnancy, based on medical evidence given by virological examination and ultrasound study of fetus and placenta. Again we emphasize that congenital cytomegalovirus infection occurs almost exclusively in children whose mothers during pregnancy for the first time infected by cytomegalovirus, but are not native speakers. The fact that the primary infection in pregnant women have no antibodies to cytomegalovirus, and therefore unmitigated cytomegalovirus quite easily crosses the placenta and affect the fetus, infection which occurs in this case almost half of the cases. To prevent primary infection, pregnant women are advised to limit social contacts, especially with children. The latter may be suffering from a form of congenital CMV and excrete the virus into the environment to 5 years. If antibodies to cytomegalovirus in pregnant women have been, then things are moving a little differently. Aggravation of the old cytomegalovirus infection, which may occur during pregnancy due to weakening of the immunity of a pregnant woman in the presence of concomitant disease or immunity-suppressing drugs, also affect the fetus. But in this case, the risk of congenital cytomegalovirus in a child less than in the case of primary infection, as antibodies, the exhausted mother's body hidden in the mother's virus infection, weaken cytomegalovirus. And in this case, fetal infection occurs much less often – only in 1-2% of cases, and the consequences of infection are not so disastrous. As the organism most pregnant women, the acute CMV infection can manifest Light influenza-like phenomena with a low temperature, general malaise, which are quite common for many other respiratory infections. However, most pregnant women are cytomegalovirus infection is asymptomatic and latent CMV can be detected only through laboratory tests. Accurate diagnosis in this case is put on the analysis of blood for intrauterine infection, where in addition to IgG to cytomegalovirus (typical for carriers) will be determined and IgM ( «Fresh" immunoglobulins, which appear only during acute process). A pregnant woman with acute cytomegalovirus infection or primary infection prescribe anti-virals and immunomodulators. If treatment is to start on time, the child's risk of infection can be minimized. If a pregnant woman is a passive carrier of cytomegalovirus, the treatment she is not nominated, but recommends that further efforts to maintain a normal immunity. If a child is born with a congenital form of visceral disease, gynecologists are encouraged to plan the next pregnancy is not earlier than 2 years. Until now, our state is that cytomegalovirus infection is a rare disease in pregnant women, and analysis for antibodies to cytomegalovirus in the overall program survey of pregnant women are not included. Therefore, to protect her pregnancy, it is necessary to show awareness and spend a little money – to pass tests required when planning pregnancy.